A man has used thought alone to control nanorobots inside a living creature for the first time. The technology released a drug inside cockroaches in response to the man’s brain activity – a technique that may be useful for treating brain disorders such as schizophrenia and ADHD.
Getting drugs to where they need to be exactly when you want them is a challenge. Most drugs diffuse through the blood stream over time – and you’re stuck with the side effects until the drug wears off.
Now, a team at the Interdisciplinary Center, in Herzliya, and Bar Ilan University, in Ramat Gan, both in Israel, have developed a system that allows precise control over when a drug is active in the body.
The group has built nanorobots out of DNA, forming shell-like shapes that drugs can be tethered to. The bots also have a gate, which has a lock made from iron oxide nanoparticles. The lock opens when heated using electromagnetic energy, exposing the drug to the environment. Because the drug remains tethered to the DNA parcel, a body’s exposure to the drug can be controlled by closing and opening the gate.
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