After more than 12 hours, police had finished about 60% to 70% of their search of suburban Watertown, said Col. Timothy Alben of the Massachusetts State Police.
Police officers in full body armor, carrying automatic weapons, flooded the area, traveling the streets in convoys and going door-to-door to track the suspect down.
It was unclear how long the manhunt would go on disrupting the lives of the millions in Boston.
Already, the Boston Red Sox announced they were postponing Friday night's game against the Kansas City Royals "to support efforts of law enforcement officers." The Boston Bruins and a Big Apple Circus performance -- both scheduled for Friday night -- also were postponed due to the ongoing manhunt, Boston police tweeted.
Police ordered businesses in the suburb of Watertown and nearby communities to stay closed and told residents to stay inside and answer the door for no one but authorities. Boston authorities advised the same. The city's subway, bus, Amtrak train systems and Greyhound and Bolt Bus -- a regional carrier -- have been shut down. Taxi service across the city also was suspended for time during the manhunt. Every Boston area school is closed.
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